GPU: SCENIC gene-regulatory network inference (disk-backed)

GPU equivalent of bixverse::rs_scenic_grn. Reads the target genes from disk in chunks and dispatches per-batch tree fits to the WGPU backend. GBM is not supported on GPU; use the CPU version.

Usage

rs_scenic_grn_gpu(
  f_path_genes,
  cell_indices,
  gene_indices,
  tf_indices,
  scenic_params,
  wave_byte_budget,
  seed,
  verbose
)

Arguments

f_path_genes

String. Path to the counts_genes.bin file.

cell_indices

Integer vector. 0-indexed positions of cells to include.

gene_indices

Integer vector. 0-indexed positions of target genes.

tf_indices

Integer vector. 0-indexed positions of TF predictors.

scenic_params

Named list. See bixverse::params_scenic().

wave_byte_budget

Double. VRAM ceiling for per-wave histogram + cumulative tensors (bytes). Default 4 GiB.

seed

Integer. Random seed.

verbose

Integer. 0L - quiet; 1L - normal; 2L - detailed.

Value

A gene x TF importance matrix.