Diffuse seed genes over a network — diffuse_seed

This function takes a diffusion vector and leverages personalised page-rank diffusion to identify influential nodes. These can be used subsequently for community detection or check AUROC values given a set of genes.

Usage

diffuse_seed_nodes(
  object,
  diffusion_vector,
  summarisation = c("max", "mean", "harmonic_sum")
)

Arguments

object: NetworkDiffusions object. The underlying class NetworkDiffusions().
diffusion_vector: Named nuermic. A named vector with values to use for the reset parameter in the personalised page-rank diffusion. Names should represent node names of the graph.
summarisation: String. If there are duplicated names in the diffusion_vector how to summarise the scores.

Value

The class with added diffusion score based on a single set of seed genes. Additionally, the seed genes are stored in the class.