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Generate reciprocal best hits based on correlations

rs_rbh_cor.Rd

This function takes list of (named) matrices which represent for example matrix factorisation results you wish to identify reciprocal best hits (RBH) for. The rows need to represent the features and the columns the parts you wish to calculate the RBH for.

Usage

rs_rbh_cor(module_matrices, spearman, min_similarity)

Arguments

module_matrices

A list of named matrices. Rows represent features and columns the samples you wish to calculate the correlations for.

spearman

Shall Spearman correlation be used.

min_similarity

Minimum (absolute) correlations that needs to exist between two terms.

Value

A list containing:

  • origin - The name of the origin of the gene modules.

  • target - The name of the target of the gene modules.

  • comparisons - Integer vector indicating how many RBH hits were identified in this comparison

  • origin_modules - Names of the gene modules from the origin.

  • target_modules - Names of the gene modules from the target.

  • similarity - The similarities between the two respective gene modules.