Calculate VISION pathway scores in Rust

The function will take in a list of gene sets that contains lists of "pos" and "neg" gene indices (0-indexed). You don't have to provide the "neg", but it can be useful to classify the delta of two stats (EMT, Th1; Th2) etc.

Usage

rs_vision(f_path, gs_list, cells_to_keep, streaming, verbose)

Arguments

f_path

String. Path to the counts_cells.bin file.

gs_list

Nested list. Each sublist contains the (0-indexed!) positive and negative gene indices of that specific gene set.

cells_to_keep

Integer. Vector of indices of the cells to keep.

streaming

Boolean. Shall the data be streamed.

verbose

Boolean. Controls verbosity of the function.

Value

A matrix of cells x vision scores per gene set.