Identify hotspot gene clusters

Identify hotspot gene clusters

Usage

generate_hotspot_membership(x, fdr_threshold = 0.05, min_size = 10L)

# S3 method for class 'Hotspot'
generate_hotspot_membership(x, fdr_threshold = 0.05, min_size = 10L)

Arguments

x

An object to generate the hotspot gene clusters for.

fdr_threshold

Numeric. The maximum FDR for a given gene-gene local correlation to be included.

min_size

Integer. Minimum cluster size.

Examples

# cluster the local gene-gene correlations into modules
sc <- demo_single_cells()
hs <- hotspot_gene_cor_sc(sc, .verbose = FALSE)
generate_hotspot_membership(hs)
#> Hotspot gene-gene local correlation results
#>   Genes: 50
#>   Cells: 500
#>   Modules: 3 (31 genes assigned, 19 unassigned)

unlink(sc@dir_data, recursive = TRUE, force = TRUE)