Calculates the TOM over an affinity matrix

Calculates the topological overlap measure for a given affinity matrix x. Has the option to calculate the signed and unsigned version.

Usage

rs_tom(x, tom_type, signed)

Arguments

x

Numerical matrix. Affinity matrix.

tom_type

String. One of c("v1", "v2") - pending on choice, a different normalisation method will be used.

signed

Boolean. Shall the signed TOM be calculated, i.e. the connectivity be taken over absolute affinities. If set to FALSE, values should be >= 0.

Value

Returns the TOM matrix.